an anti-inflammatory drug that fights pain and blocks Cox-2 activity without impeding the activity of Cox-1; increases the risk of heart attacks - Cox-2 inhibitors reduce the symptoms of arthritis without endangering the stomach and kidneys • Hypernyms: anti-inflammatory, anti-inflammatory drug • Hyponyms: celecoxib, Celebrex, rofecoxib, Vioxx, valdecoxib, Bextra